Completely powered down the host and after powering back up a single VM won't start with the error it can't find its vmx file.
I can Register and Unregister the vm just fine. I can also navigate to the directory, list it, download it, edit it, write to it, etc.
[root@esxi:/vmfs/volumes] find . -name nFVE01.vmx -print
./5c6a1cfb-2138bffb-a4e7-003ee1c983b8/nFVE01/nFVE01.vmx
find: ./5c6a1cfb-2138bffb-a4e7-003ee1c983b8/nFVE01/nFVE01.vmx.lck: No such file or directory
find: ./5c6a1cfb-2138bffb-a4e7-003ee1c983b8/nFVE01/nFVE01.vmx~: No such file or directory
find: ./5c6a1cfb-2138bffb-a4e7-003ee1c983b8/nFVE01/nFVE01-ebbf2e48.vswp: No such file or directory
[root@esxi:/vmfs/volumes] cd ./5c6a1cfb-2138bffb-a4e7-003ee1c983b8/nFVE01
[root@esxi:/vmfs/volumes/5c6a1cfb-2138bffb-a4e7-003ee1c983b8/nFVE01] ls -la
ls: ./nFVE01.vmx.lck: No such file or directory
ls: ./nFVE01.vmx~: No such file or directory
ls: ./nFVE01-ebbf2e48.vswp: No such file or directory
total 9152768
drwxr-xr-x 1 root root 73728 Jul 7 21:35 .
drwxr-xr-t 1 root root 77824 Jul 7 21:31 ..
-rw------- 1 root root 620692480 Jun 28 14:17 nFVE01-flat.vmdk
-rw------- 1 root root 8684 Jun 28 14:17 nFVE01.nvram
-rw------- 1 root root 470 Feb 22 14:54 nFVE01.vmdk
-rw-r--r-- 1 root root 0 Feb 22 14:54 nFVE01.vmsd
-rwxr-xr-x 1 root root 4325 Jul 7 21:56 nFVE01.vmx
-rw------- 1 root root 154 Feb 22 15:38 nFVE01.vmxf
-rw------- 1 root root 268435456000 Jun 28 14:17 nFVE01_1-flat.vmdk
-rw------- 1 root root 476 Feb 22 14:55 nFVE01_1.vmdk
-rw-r--r-- 1 root root 256934562 Jun 28 14:17 vmware.log
-rw------- 1 root root 115343360 Feb 22 14:54 vmx-nFVE01-3955174984-1.vswp
[root@esxi:/vmfs/volumes/5c6a1cfb-2138bffb-a4e7-003ee1c983b8/nFVE01]